Medicines to treat Systemic Lupus Erythematosus

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Systemic lupus erythematosus is autoimmune disease, damaging several systems and organs of the body, such as skin, joints, heart, kidney, central nervous system and blood system. Patients will suffer from many symptoms. There are also various kinds of medicines to treat the disease.
1. Nonsteroidal anti-inflammatory drugs
These drugs, such as aspirin, indometacin and fenbid, are commonly used in treating the mild symptoms of systemic lupus erythematosus. There are many side effects of the drugs, some of which are easily confused with the symptoms of systemic lupus erythematosus. But some of the damage could be cured.
2. Antimalarial drugs
These drugs like chloroquine and hydroxychloroquine are used to control the systemic symptoms, rash, muscle pain and joint pain. Generally, these drugs have a better tolerance. But the main side effects are eyes toxicity. If patients take those pills, they should check the eyes before or after the treatment for three months.
3. Glucocorticoid
Glucocorticoid is the main medicine to treat SLE, but with lots of side effects. Metacortandracin is the most common used medicine to treat the disease. The used doses are: small dose <30mg/d, medium dose 30～50mg/d, and large dose >50mg/d. In the acute and activity stage, patients could take the medicines in times. After the lesions are stable, patients could take once in a day. Oral taking 5～20mg/d Metacortandracin could help to treat the systemic symptoms, skin damage, serositis, joint and muscle damage and so on.
If patients suffer from sever symptoms, such as nephritis, brain disease, vasculitis, blood system and lung damage, they could intravenously drip large dose of metacortandracin or methylprednisolone 0.5-1.0g/d for three days. After that oral take metacortandracin 60-80mg/d. When the disease is stable, decrease the dose gradually based on the lesions to keep the treatment.

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